N-Acetylcysteine (NAC) and its Immunomodulatory Properties

Despite the increasing interest and use of NAC over decades, there remains much debate surrounding NAC’s mechanisms action. It was widely believed that exerts its antioxidant cytoprotective properties through ability to act as a scavenger reactive oxygen species, precursor for glutathione biosynthesis, disulfide reductant. However, these three major narratives are only applicable under specific circumstances cannot explain actions in more general context. A newly emerging alternative mechanism action involving hydrogen sulfide sulfane sulfur species may serve provide an explanation effects generalized Part II this review will overview molecular